Prostaglandin D2 methyl ester

Prostaglandin D2 methyl ester
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008385-500 500 µg -

3 - 10 business days*

43.00€
Cay10008385-1 1 mg -

3 - 10 business days*

82.00€
Cay10008385-5 5 mg -

3 - 10 business days*

340.00€
 
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large... more
Product information "Prostaglandin D2 methyl ester"
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis. It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation. Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2. It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2. Formal Name: 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid, methyl ester. CAS Number: 49852-81-5. Synonyms: PGD2 methyl ester. Molecular Formula: C21H34O5. Formula Weight: 366.5. Purity: >97%. Formulation: A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1C/C=C\CCCC(=O)OC. InChi Code: InChI=1S/C21H34O5/c1-3-4-7-10-16(22)13-14-18-17(19(23)15-20(18)24)11-8-5-6-9-12-21(25)26-2/h5,8,13-14,16-19,22-23H,3-4,6-7,9-12,15H2,1-2H3/b8-5-,14-13+/t16-,17+,18+,19-/m0/s1. InChi Key: WNBMQMMGBBWUOZ-BYNKDMOPSA-N.
Keywords: PGD2 methyl ester, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid, methyl ester
Supplier: Cayman Chemical
Supplier-Nr: 10008385

Properties

Application: Bioactive lipid assays
MW: 366.5 D
Formula: C21H34O5
Purity: >97%
Format: Solution

Database Information

CAS : 49852-81-5| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336, H360
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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