POV-PC

POV-PC
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10031-1 1 mg -

5 - 10 business days*

90.00€
Cay10031-5 5 mg -

5 - 10 business days*

405.00€
Cay10031-10 10 mg -

5 - 10 business days*

720.00€
Cay10031-25 25 mg -

5 - 10 business days*

1,575.00€
 
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are... more
Product information "POV-PC"
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. 1-(Palmitoyl)-2-(5-oxovaleroyl)-phosphatidylcholine, or POV-PC, is one of the oxLDL species derived from 2-arachidonoyl or eicosapentanoyl phospholipids. POV-PC confers CD36 scavenger receptor binding affinity more potently than any hydroperoxy PC species, and may be one of the more important structural determinants of oxLDL. Treatment of cultured endothelial cells with POV-PC stimulates monocyte binding, stimulates intracellular cAMP production, and strongly inhibits the LPS-induced binding of neutrophils. Formal Name: 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphatidylcholine. CAS Number: 121324-31-0. Synonyms: 2-(5-oxovaleryl) Phosphatidylcholine. Molecular Formula: C29H56NO9P. Formula Weight: 593.7. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: 15 mg/ml, DMSO: 10 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N](C)(C)C)OC(=O)CCCC=O. InChi Code: InChI=1S/C29H56NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-20-28(32)36-25-27(39-29(33)21-18-19-23-31)26-38-40(34,35)37-24-22-30(2,3)4/h23,27H,5-22,24-26H2,1-4H3/t27-/m1/s1. InChi Key: RKIDALSACBQVTN-HHHXNRCGSA-N. Side Chain Carbon Sum: 21:0.
Keywords: 2-(5-oxovaleryl) Phosphatidylcholine, 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphatidylcholine
Supplier: Cayman Chemical
Supplier-Nr: 10031

Properties

Application: Bioactive lipid assays
MW: 593.7 D
Formula: C29H56NO9P
Purity: >98%
Format: Solution

Database Information

CAS : 121324-31-0| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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