C24:1 Ceramide (d18:1/24:1(15Z))

Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase. C24:1 Ceramide (d18:1/24:1(15Z)) is one of the most abundant naturally occurring ceramides. Ceramides mediate many diverse biological activities, as has been demonstrated in studies utilizing cell-permeable ceramide analogs. A few of the processes regulated by ceramides include apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain.Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-15Z-tetracosenamide. CAS Number: 54164-50-0. Synonyms: Ceramide (d18:1/24:1(15Z)), Cer(d18:1/24:1(15Z)), Nervonic Ceramide, N-Nervonoyl-D-erythro-Sphingosine. Molecular Formula: C42H81NO3. Formula Weight: 648.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: Slightly soluble, Ethanol: 1 mg/ml, Ethanol:PBS (pH 7.2)(1:1): 0.5 mg/ml, PBS pH 7.2: Slightly soluble. SMILES: OC[C@H](NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@H](O)/C=C/CCCCCCCCCCCCC. InChi Code: InChI=1S/C42H81NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-42(46)43-40(39-44)41(45)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,35,37,40-41,44-45H,3-16,19-34,36,38-39H2,1-2H3,(H,43,46)/b18-17-,37-35+/t40-,41+/m0/s1. InChi Key: VJSBNBBOSZJDKB-KPEYJIHVSA-N.