Leukotriene E4 methyl ester

Leukotriene E4 methyl ester
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007166-25 25 µg -

5 - 10 business days*

99.00€
Cay10007166-50 50 µg -

5 - 10 business days*

188.00€
Cay10007166-100 100 µg -

5 - 10 business days*

355.00€
 
Leukotriene E4 (LTE4) is produced by the action of a dipeptidase on LTD4 leaving only the... more
Product information "Leukotriene E4 methyl ester"
Leukotriene E4 (LTE4) is produced by the action of a dipeptidase on LTD4 leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities characteristic of cysteinyl LTs. Unlike LTC4 and LTD4, LTE4 accumulates in both plasma and urine. Therefore, urinary excretion of LTE4 is most often used as an indicator of asthma. LTE4 methyl ester is a more lipid soluble form of LTE4. The biological activity of LTE4 methyl ester has not been reported. Formal Name: 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid, methyl ester. Synonyms: LTE4 methyl ester. Molecular Formula: C24H39NO5S. Formula Weight: 453.6. Purity: >97%. Formulation: A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): .1 mg/ml. lambdamax: 281 nm. SMILES: CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](N)C(O)=O)[C@H](O)CCCC(OC)=O. InChi Code: InChI=1S/C24H39NO5S/c1-3-4-5-6-7-8-9-10-11-12-13-14-17-22(31-19-20(25)24(28)29)21(26)16-15-18-23(27)30-2/h7-8,10-14,17,20-22,26H,3-6,9,15-16,18-19,25H2,1-2H3,(H,28,29)/b8-7-,11-10-,13-12+,17-14+/t20?,21-,22+/m0/s1. InChi Key: FIXJQRIEAIDXEN-RFOUKSCXSA-N.
Keywords: LTE4 methyl ester, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid, methyl ester
Supplier: Cayman Chemical
Supplier-Nr: 10007166

Properties

Application: Bioactive lipid assays
MW: 453.6 D
Formula: C24H39NO5S
Purity: >97%
Format: Solution

Database Information

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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