Leukotriene D4-d5

Leukotriene D4-d5
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10006199-25 25 µg -

6 - 10 business days*

390.00€
Cay10006199-50 50 µg -

6 - 10 business days*

740.00€
Cay10006199-100 100 µg -

6 - 10 business days*

1,324.00€
 
Leukotriene D4-d5 (LTD4-d5) is intended for use as an internal standard for the quantification of... more
Product information "Leukotriene D4-d5"
Leukotriene D4-d5 (LTD4-d5) is intended for use as an internal standard for the quantification of LTD4 (Cay-20310) by GC- or LC-MS. LTD4 is an active metabolite of LTC4 (Cay-20210) and a constituent of slow-reacting substance of anaphylaxis (SRS-A). It is formed via metabolism of LTC4 by gamma-glutamyl transpeptidase. Like LTC4, LTD4 (0.01-0.1 pM) induces contractions in isolated guinea pig parenchymal strips and tracheal spirals. In vivo, LTD4 increases insufflation pressure, a marker of bronchoconstriction, in anesthetized guinea pigs by 100% when administered at a dose of 89 pmol per animal. It also increases vascular permeability in guinea pig skin when administered intradermally at a dose of 0.1 pmol per animal.Formal Name: S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl-14,14,15,15,15-d5]-L-cysteinyl-glycine. CAS Number: 1240398-17-7. Synonyms: LTD4-d5. Molecular Formula: C25H35D5N2O6S. Formula Weight: 501.7. Purity: >99% deuterated forms (d1-d5). Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 1 mg/ml, PBS (pH 7.2): .1 mg/ml. lambdamax: 280 nm. SMILES: N[C@H](C(NCC(O)=O)=O)CS[C@@H]([C@@H](O)CCCC(O)=O)/C=C/C=C/C=C\C/C=C\CCCC([2H])([2H])C([2H])([2H])[2H]. InChi Code: InChI=1S/C25H40N2O6S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22(21(28)15-14-17-23(29)30)34-19-20(26)25(33)27-18-24(31)32/h6-7,9-13,16,20-22,28H,2-5,8,14-15,17-19,26H2,1H3,(H,27,33)(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t20-,21-,22+/m0/s1/i1D3,2D2. InChi Key: YEESKJGWJFYOOK-HXHZKDJLSA-N.
Keywords: LTD4-d5, S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl-14,14,15,15,15-d5]-L-cysteinyl-glycine
Supplier: Cayman Chemical
Supplier-Nr: 10006199

Properties

Application: Standard
MW: 501.7 D
Formula: C25H35D5N2O6S
Purity: >99% deuterated forms (d1-d5)
Format: Solution

Database Information

CAS : 1240398-17-7| Matching products

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H333
P Phrases: P210, P233, P240, P241, P242, P243, P264, P280, P303+361+353, P304+312, P305+351+338, P337+313, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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