Leukotriene A3 methyl ester

Biosynthesis of LTA3 occurs from 5,8,11-eicosatrienoic acid via the 5-LO pathway and it is the putative intermediate in the biosynthesis of 3-series leukotrienes. LTA3 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed. Formal Name: 5S-trans-5,6-oxido-7E,9E,11Z-eicosatrienoic acid, methyl ester. CAS Number: 83851-38-1. Synonyms: LTA3 methyl ester. Molecular Formula: C21H34O3. Formula Weight: 334.5. Purity: >97%. Formulation: A solution in hexane containing 1% triethylamine. Solubility: DMF: >50 mg/ml (per Rao Maddipati), DMSO: >50 mg/ml (per Rao Maddipati), Ethanol: >50 mg/ml (per Rao Maddipati), PBS pH 7.2: >1 mg/ml (from 13(S)-HODE). lambdamax: 279 nm. SMILES: CCCCCCCC/C=C\C=C\C=C\[C@H]1[C@@H](O1)CCCC(OC)=O. InChi Code: InChI=1S/C21H34O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-16-19-20(24-19)17-15-18-21(22)23-2/h10-14,16,19-20H,3-9,15,17-18H2,1-2H3/b11-10-,13-12+,16-14+/t19-,20-/m0/s1. InChi Key: YOAQIJHBMIIBJM-NLAMMTFYSA-N.