Latanoprost Lactone Diol

Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Latanoprost lactone diol is an intermediate in the synthesis of latanoprost. Latanoprost lactone diol can be converted to the free acid of latanoprost by reduction with DIBAL followed by Wittig reaction with commercially available reagents.Formal Name: (3aR,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(3R)-3-hydroxy-5-phenylpentyl]-2H-cyclopenta[b]furan-2-one. CAS Number: 145667-75-0. Molecular Formula: C18H24O4. Formula Weight: 304.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): .3 mg/ml. lambdamax: 208 nm. SMILES: O[C@@H]1C[C@H]2[C@H](CC(O2)=O)[C@H]1CC[C@@H](O)CCC3=CC=CC=C3. InChi Code: InChI=1S/C18H24O4/c19-13(7-6-12-4-2-1-3-5-12)8-9-14-15-10-18(21)22-17(15)11-16(14)20/h1-5,13-17,19-20H,6-11H2/t13-,14+,15+,16+,17-/m0/s1. InChi Key: CQVHXVLSHMRWEC-UTSKFRMZSA-N.