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Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are... more
Product information "KDdiA-PC"
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. KDdiA-PC is one of the most potent CD36 ligands among the oxLDL species. KDdiA-PC confers CD-36 scavenger receptor binding affinity to LDL at a frequency of only two to three KDdiA-PC molecules/LDL particle, and may be one of the more important structural determinants of oxLDL. Formal Name: 1-palmitoyl-2-(4-keto-dodec-3-ene-dioyl)phosphatidylcholine. CAS Number: 439904-34-4. Molecular Formula: C36H66NO11P. Formula Weight: 719.9. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: .5 mg/ml, DMSO: .5 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: CCCCCCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCC(/C=C/C(O)=O)=O)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O. InChi Code: InChI=1S/C36H66NO11P/c1-5-6-7-8-9-10-11-12-13-14-15-18-21-24-35(41)45-30-33(31-47-49(43,44)46-29-28-37(2,3)4)48-36(42)25-22-19-16-17-20-23-32(38)26-27-34(39)40/h26-27,33H,5-25,28-31H2,1-4H3,(H-,39,40,43,44)/b27-26+/t33-/m1/s1. InChi Key: XWKBYMQTSGGZLW-PHSKOSPPSA-N. Side Chain Carbon Sum: 28:1.
Keywords: | 1-palmitoyl-2-(4-keto-dodec-3-ene-dioyl)phosphatidylcholine |
Supplier: | Cayman Chemical |
Supplier-Nr: | 62935 |
Properties
Application: | Bioactive lipid assays |
MW: | 719.9 D |
Formula: | C36H66NO11P |
Purity: | >98% |
Format: | Solution |
Database Information
CAS : | 439904-34-4| Find alternatives |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -80°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: | ![]() |
H Phrases: | H225 |
P Phrases: | P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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