Asialo Ganglioside GM2

Asialo ganglioside GM2 (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal beta-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. This product contains asialo ganglioside GM2 molecular species with variable fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid. [Matreya, LLC. Catalog No. 1512]Formal Name: 1-O-[O-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl-(1->4)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide. CAS Number: 35960-33-9. Synonyms: Asialo-GM2, Asialoganglioside GM2, Gangliotriaosylceramide. Molecular Formula: C56H104N2O18 (for stearoyl). Formula Weight: 1093.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Chloroform:Methanol:Water (2:1:0.1): Soluble. SMILES: [R]C(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)CO[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@]2([H])O[C@H](CO)[C@H](O[C@@]3([H])[C@H](NC(C)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)[C@H](O)[C@H]2O)[C@@H](CO)O1)=O.