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Docosatrienoic acid is a rare omega-3 fatty acid not readily detected in normal phospholipid PUFA... more
Product information "Docosatrienoic Acid"
Docosatrienoic acid is a rare omega-3 fatty acid not readily detected in normal phospholipid PUFA pools. It is a polyunsaturated version of the fatty acid docosanoic acid (Cay-9000338). Docosatrienoic acid inhibits [3H]-LTB4 binding to pig neutrophils at a concentration of 5 µM. It also dose-dependently inhibits the activity of mammalian DNA polymerases and human topoisomerases I and II, potentially by binding directly to the hydrophobic region of the enzymes. The cis configuration of the double bonds is important for this activity, and the carboxyl group is required as the methyl ester version has no activity at these enzymes.Formal Name: 13Z,16Z,19Z-docosatrienoic acid. CAS Number: 28845-86-5. Synonyms: cis-13,16,19-Docosatrienoic Acid. Molecular Formula: C22H38O2. Formula Weight: 334.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: 0.15 M Tris-HCl pH 8.5: >1 mg/ml (from Oleic Acid), DMF: >100 mg/ml (from Oleic Acid), DMSO: >100 mg/ml (from Oleic Acid), Ethanol: >100 mg/ml (from Oleic Acid), PBS pH 7.2: <100 µg/ml (from Oleic Acid). SMILES: CC/C=C\C/C=C\C/C=C\CCCCCCCCCCCC(=O)O. InChi Code: InChI=1S/C22H38O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10H,2,5,8,11-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-. InChi Key: WBBQTNCISCKUMU-PDBXOOCHSA-N. Side Chain Carbon Sum: 22:3.
Keywords: | cis-13,16,19-Docosatrienoic Acid, 13Z,16Z,19Z-docosatrienoic acid |
Supplier: | Cayman Chemical |
Supplier-Nr: | 90170 |
Properties
Application: | Bioactive lipid assays |
MW: | 334.5 D |
Formula: | C22H38O2 |
Purity: | >98% |
Format: | Solution |
Database Information
CAS : | 28845-86-5| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H225, H319 |
P Phrases: | P210, P233, P240, P241, P242, P243, P264, P280, P303+361+353, P305+351+338, P337+313, P370+378, P403+235, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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