Delta17-6-keto Prostaglandin F1alpha

Delta17-6-keto Prostaglandin F1alpha (Delta17-6-keto PGF1alpha) is a cyclooxygenase (COX) product of eicosapentaenoic acid (EPA) in various tissues such as seminal vesicles, lung, Polymorphonuclear leukocytes, and ocular tissues. Delta17-6-keto PGF1alpha and other 3-series COX products from EPA, such as PGF3alpha, PGE3, and thromboxane B3, may be involved in the reduced incidence of glaucoma in patients on a marine-rich (EPA-rich) diet.Formal Name: 6-oxo-9alpha,11alpha,15S-trihydroxy-prosta-13E,17Z-dien-1-oic acid. CAS Number: 68324-95-8. Synonyms: omega-3 6-keto PGF2alpha. Molecular Formula: C20H32O6. Formula Weight: 368.5. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: >50 mg/ml (from PGF1a), DMSO: >50 mg/ml (from PGF1a), Ethanol: >75 mg/ml (from PGF1a), PBS pH 7.2: >2.1 mg/ml (from PGF1a). SMILES: O[C@@H]1[C@H](CC(CCCCC(O)=O)=O)[C@@H](/C=C/[C@@H](O)C/C=C\CC)[C@H](O)C1. InChi Code: InChI=1S/C20H32O6/c1-2-3-4-7-14(21)10-11-16-17(19(24)13-18(16)23)12-15(22)8-5-6-9-20(25)26/h3-4,10-11,14,16-19,21,23-24H,2,5-9,12-13H2,1H3,(H,25,26)/b4-3-,11-10+/t14-,16+,17+,18+,19-/m0/s1. InChi Key: HFKNJQYMAGMXTR-CAPHXMBKSA-N.