(+)-Cloprostenol (sodium salt)

(+)-Cloprostenol (sodium salt)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16766-1 1 mg -

3 - 10 business days*

73.00€
Cay16766-5 5 mg -

3 - 10 business days*

327.00€
Cay16766-10 10 mg -

3 - 10 business days*

580.00€
 
(+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol.... more
Product information "(+)-Cloprostenol (sodium salt)"
(+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol. (+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. Cloprostenol is 200 times and 100 times more potent than PGF2alpha in terminating pregnancy in hamsters and rats, respectively without the side effects associated with PGF2alpha. The subcutaneous dose required for interrupting early pregnancy is species dependent, requiring approximately 1.25 µg/kg and 270 µg/kg in hamsters and rats, respectively. Cloprostenol is also a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 of 3 x 10-12 M. Formal Name: (+)-9alpha,11alpha,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, monosodium salt. CAS Number: 62561-03-9. Synonyms: D-Cloprostenol, (+)-16-m-chlorophenoxy tetranor PGF2alpha, (+)-16-m-chlorophenoxy tetranor Prostaglandin F2alpha. Molecular Formula: C22H28ClO6 . Na. Formula Weight: 446.9. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 130 mg/ml, DMSO: 60 mg/ml, Ethanol: 50 mg/ml, PBS (7.2): 35 mg/ml. lambdamax: 275, 282 nm. SMILES: O[C@@H]1[C@H](C/C=C\CCCC([O-])=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC(Cl)=C2)[C@H](O)C1.[Na+]. InChi Code: InChI=1S/C22H29ClO6.Na/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28,/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28),/q,+1/p-1/b3-1-,11-10+,/t16-,18-,19-,20+,21-,/m1./s1. InChi Key: IFEJLMHZNQJGQU-KXXGZHCCSA-M.
Keywords: (+)-16-m-chlorophenoxy tetranor PGF2alpha, (+)-16-m-chlorophenoxy tetranor Prostaglandin F2alpha, D-Cloprostenol, (+)-9alpha,11alpha,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, monosodium salt
Supplier: Cayman Chemical
Supplier-Nr: 16766

Properties

Application: Bioactive lipid assays
MW: 446.9 D
Formula: C22H28ClO6 . Na
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 62561-03-9| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302
P Phrases: P264, P270, P301+310, P330, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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