(+)-Cloprostenol

(+)-Cloprostenol
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16765-1 1 mg -

3 - 10 business days*

73.00€
Cay16765-5 5 mg -

3 - 10 business days*

327.00€
Cay16765-10 10 mg -

3 - 10 business days*

580.00€
 
(+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor... more
Product information "(+)-Cloprostenol"
(+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent than PGF2alpha in terminating pregnancy when given subcutaneously at a daily dose of 0.125 µg/kg in rats and hamsters, without the side effects associated with PGF2alpha. (+)-Cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an IC50 value of 3 pM. Formal Name: (+)-9alpha,11alpha,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid. CAS Number: 54276-21-0. Synonyms: D-Cloprostenol, (+)-16-m-chlorophenoxy tetranor PGF2alpha, (+)-16-m-chlorophenoxy tetranor Prostaglandin F2alpha. Molecular Formula: C22H29ClO6. Formula Weight: 424.9. Purity: >97%. Formulation: A solution in ethanol. Solubility: DMF: >100 mg/ml (from Fluprostenol), DMSO: >100 mg/ml (from Fluprostenol, Ethanol: >100 mg/ml (from Fluprostenol), PBS pH 7.2: >16 mg/ml (from Fluprostenol). lambdamax: 220, 275, 282 nm. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)COC2=CC=CC(Cl)=C2)[C@H](O)C1. InChi Code: InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m1/s1. InChi Key: VJGGHXVGBSZVMZ-QIZQQNKQSA-N.
Keywords: (+)-16-m-chlorophenoxy tetranor PGF2alpha, (+)-16-m-chlorophenoxy tetranor Prostaglandin F2alpha, D-Cloprostenol, (+)-9alpha,11alpha,15R-trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 16765

Properties

Application: FP receptor agonist
MW: 424.9 D
Formula: C22H29ClO6
Purity: >97%
Format: Solution

Database Information

CAS : 54276-21-0| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H360
P Phrases: P201, P202, P210, P233, P240, P241, P242, P243, P280, P303+361+353, P308+313, P370+378, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "(+)-Cloprostenol"
Write a review
or to review a product.
Viewed