Carbocyclic Thromboxane A2

Carbocyclic Thromboxane A2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay19010-100 100 µg -

6 - 10 business days*

Cay19010-500 500 µg -

6 - 10 business days*

Cay19010-1 1 mg -

6 - 10 business days*

CTA2 is a stable analog of TXA2. CTA2 is a potent coronary vasoconstrictor and is effective at... more
Product information "Carbocyclic Thromboxane A2"
CTA2 is a stable analog of TXA2. CTA2 is a potent coronary vasoconstrictor and is effective at concentrations as low as 1 nM in cat coronary arteries. Unlike other vascular TP receptor agonists, CTA2 is a potent inhibitor of prostanoid-induced platelet aggregation. It inhibits arachidonic acid-induced aggregation with an IC50 value of 4-5 µM. CTA2 also exhibits selective and dose-dependent inhibition of TXB2 synthesis in rabbit platelets at concentrations between 1 and 100 µM. Formal Name: 9alpha,11alpha-methylene-15S-hydroxy-11a-deoxy-11a-methylene-thromba-5Z,13E-dien-1-oic acid. CAS Number: 74034-56-3. Synonyms: Carbocyclic TXA2, CTA2. Molecular Formula: C22H36O3. Formula Weight: 348.5. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: >50 mg/ml (from Pinane TXA2), DMSO: >25 mg/ml (from Pinane TXA2), Ethanol: >100 mg/ml (from Pinane TXA2), PBS pH 7.2: >100 µg/ml (from Pinane TXA2). SMILES: CCCCC[C@H](O)/C=C/[C@H]1C[C@H]2C[C@H](C2)[C@@H]1C/C=C\CCCC(O)=O. InChi Code: InChI=1S/C22H36O3/c1-2-3-6-9-20(23)13-12-18-14-17-15-19(16-17)21(18)10-7-4-5-8-11-22(24)25/h4,7,12-13,17-21,23H,2-3,5-6,8-11,14-16H2,1H3,(H,24,25)/b7-4-,13-12+/t17-,18-,19+,20-,21+/m0/s1. InChi Key: ZIWNJZLXPXFNGN-JJPTUHNDSA-N.
Keywords: Carbocyclic TXA2, CTA2, 9alpha,11alpha-methylene-15S-hydroxy-11a-deoxy-11a-methylene-thromba-5Z,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 19010


Application: TP receptor agonist
MW: 348.5 D
Formula: C22H36O3
Purity: >98%
Format: Solution

Database Information

CAS : 74034-56-3| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
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