C-8 Ceramide

C-8 Ceramide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay62540-1 1 mg -

6 - 10 business days*

Cay62540-5 5 mg -

6 - 10 business days*

Cay62540-10 10 mg -

6 - 10 business days*

Cay62540-25 25 mg -

6 - 10 business days*

C8 Ceramide (d18:1/8:0) is a cell-permeable analog of naturally occurring ceramides. Unlike C2... more
Product information "C-8 Ceramide"
C8 Ceramide (d18:1/8:0) is a cell-permeable analog of naturally occurring ceramides. Unlike C2 ceramide, it is metabolized within cells to generate natural ceramides, often causing a dramatic increase in cellular ceramide levels. For this reason, treatment of cells with C8 Ceramide (d18:1/8:0) may more closely mimic the effects of ceramide elevation than does treatment with shorter chain ceramide analogs. C8 Ceramide (d18:1/8:0) likely mediates many diverse biological activities, as do natural ceramides. It promotes the differentiation of human keratinocytes and induces apoptosis of both human leukemia cells and the U937 cell line. Formal Name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-octanamide. CAS Number: 74713-59-0. Synonyms: C8 Ceramide, Cer(d18:1/8:0), N-octanoyl-D-erythro-Sphingosine, N-Octanoylsphingosine. Molecular Formula: C26H51NO3. Formula Weight: 425.7. Purity: >98%. Formulation: A crystalline solid. Solubility: acidic PBS: <50 µg/ml, basic PBS: <50 µg/ml, DMF: >22 mg/ml, DMSO: >20 mg/ml, Ethanol: >33 mg/ml, PBS pH 7.2: <50 µg/ml. SMILES: CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCC)=O)CO. InChi Code: InChI=1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21-19+/t24-,25+/m0/s1. InChi Key: APDLCSPGWPLYEQ-WRBRXSDHSA-N.
Keywords: C8 Ceramide, Cer(d18:1/8:0), N-Octanoylsphingosine, N-octanoyl-D-erythro-Sphingosine, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-octanamide
Supplier: Cayman Chemical
Supplier-Nr: 62540


Application: Bioactive lipid assays
MW: 425.7 D
Formula: C26H51NO3
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 74713-59-0| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Our products are for laboratory research use only: Not for administration to humans!
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