Butaprost (free acid)

Butaprost (free acid)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13741-500 500 µg -

6 - 10 business days*

Cay13741-1 1 mg -

6 - 10 business days*

Cay13741-5 5 mg -

6 - 10 business days*

Cay13741-10 10 mg -

6 - 10 business days*

Butaprost is an EP2 selective agonist which has frequently been used to pharmacologically define... more
Product information "Butaprost (free acid)"
Butaprost is an EP2 selective agonist which has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Prostaglandin free acids generally bind to their cognate receptors with 10 to 100 times the affinity of the corresponding ester derivative. Consistent with this trend, butaprost binds to membranes from EP2 receptor-transfected CHO cells with a Ki value of 2,400 nM, whereas butaprost (free acid) and CAY10399 (the 2-series congener of butaprost free acid) exhibit significantly lower Ki values of 73 and 92 nM, respectively. Butaprost (free acid) is therefore another useful tool for characterizing EP receptor-mediated signalling events. Formal Name: 9-oxo-11alpha,16S-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid. CAS Number: 433219-55-7. Synonyms: (±)-15-deoxy-16S-hydroxy-17-cyclobutyl PGE1, 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1. Molecular Formula: C23H38O5. Formula Weight: 394.6. Purity: >95%. Formulation: A solution in methyl acetate. Solubility: DMF: 25 mg/ml, DMSO: 25/mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 100 µg/ml. SMILES: CCCC1(CCC1)[C@@H](O)C/C=C/[C@H]([C@H]2CCCCCCC(O)=O)[C@H](O)CC2=O. InChi Code: InChI=1S/C23H38O5/c1-2-13-23(14-8-15-23)21(26)11-7-10-18-17(19(24)16-20(18)25)9-5-3-4-6-12-22(27)28/h7,10,17-18,20-21,25-26H,2-6,8-9,11-16H2,1H3,(H,27,28)/b10-7+/t17-,18-,20-,21+/m1/s1. InChi Key: PAYNQYXOKJDXAV-ZHIWTBQHSA-N.
Keywords: (±)-15-deoxy-16S-hydroxy-17-cyclobutyl PGE1, 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1, 9-oxo-11alpha,16S-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 13741


Application: EP2 receptor agonist
MW: 394.6 D
Formula: C23H38O5
Purity: >95%
Format: Solution

Database Information

CAS : 433219-55-7| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336, H361
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
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