Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13740-500 500 µg -

6 - 10 business days*

Cay13740-1 1 mg -

6 - 10 business days*

Cay13740-5 5 mg -

6 - 10 business days*

Cay13740-10 10 mg -

6 - 10 business days*

Butaprost, a structural analog of PGE2, is a selective agonist for the EP2 receptor subtype. EP2... more
Product information "Butaprost"
Butaprost, a structural analog of PGE2, is a selective agonist for the EP2 receptor subtype. EP2 receptors are expressed on human neutrophils and on respiratory, vascular, and uterine smooth muscle. Butaprost binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor, and does not bind appreciably to any of the other murine EP receptors or DP, TP, FP, or IP receptors. The EC50 for the stimulation of cAMP by butaprost in COS cells transfected with the human EP2 receptor is about 5 µM, while the EC50 for PGE2 in this assay is about 43 nM. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Formal Name: 9-oxo-11alpha,16S-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid, methyl ester. CAS Number: 69685-22-9. Synonyms: 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1 methyl ester, TR 4979. Molecular Formula: C24H40O5. Formula Weight: 408.6. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 25 mg/ml, DMSO: 30 mg/ml, Ethanol: 50 mg/ml, Ethanol:PBS (pH 7.2)(1:3): .15 mg/ml. SMILES: O=C1[C@H](CCCCCCC(OC)=O)[C@@H](/C=C/C[C@H](O)C2(CCC2)CCC)C(O)C1. InChi Code: InChI=1S/C24H40O5/c1-3-14-24(15-9-16-24)22(27)12-8-11-19-18(20(25)17-21(19)26)10-6-4-5-7-13-23(28)29-2/h8,11,18-19,21-22,26-27H,3-7,9-10,12-17H2,1-2H3/b11-8+/t18-,19-,21?,22+/m1/s1. InChi Key: XRISENIKJUKIHD-KHAOJFLNSA-N.
Keywords: 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1 methyl ester, TR 4979, 9-oxo-11alpha,16S-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid, methyl ester
Supplier: Cayman Chemical
Supplier-Nr: 13740


Application: EP2 receptor agonist
MW: 408.6 D
Formula: C24H40O5
Purity: >98%
Format: Solution

Database Information

CAS : 69685-22-9| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336, H360
P Phrases: P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
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