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N-3-oxo-dodecanoyl-L-Homoserine lactone
Item number: Cay10007895-1
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex. It induces the production of IL-8 in 16HBE human bronchial epithelial cells when used at a concentration of 100 µM. Supernatants from...
| Keywords: | 3-oxo-C12-HSL, N-(3-oxododecanoyl) L-Homoserine lactone, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-dodecanamide |
| Application: | Bioactive lipid assays |
| CAS | 168982-69-2 |
| MW: | 297.4 D |
From 44.00€
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Prostaglandin E2-d4
Item number: Cay314010-50
Prostaglandin E2-d4 (PGE2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated...
| Keywords: | Dinoprostone-d4, PGE2-d4, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| CAS | 34210-10-1 |
| MW: | 356.5 D |
From 89.00€
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FTY720 Phosphate
Item number: Cay10008639-1
FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. In vivo, FTY720...
| Keywords: | FTY720P, 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol, 1-(dihydrogen phosphate) |
| Application: | Sphingosine analog |
| CAS | 402615-91-2 |
| MW: | 387.5 D |
From 142.00€
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Resolvin D2
Item number: Cay10007279-10
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D2 (RvD2) is produced...
| Keywords: | 7(S),16(R),17(S)-Resolvin D2, RvD2, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic acid |
| Application: | Lipid mediator |
| CAS | 810668-37-2 |
| MW: | 376.5 D |
From 205.00€
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2-Arachidonoyl Glycerol
Item number: Cay62160-1
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively). Unlike arachidonoyl ethanolamide (AEA, Cay-90050), 2-AG is present at relatively high levels in the central nervous system and is the most abundant molecular species...
| Keywords: | 2-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glyceryl ester |
| Application: | CB1 receptor agonist |
| CAS | 53847-30-6 |
| MW: | 378.6 D |
From 50.00€
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4-hydroxy Nonenal
Item number: Cay32100-1
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized omega-6 polyunsaturated fatty acids such as arachidonic acid. 4-hydroxy Nonenal is widely used as a marker of lipid peroxidation. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and...
| Keywords: | 4-HNE, (±)-4-hydroxy-2E-nonenal |
| Application: | Lipid peroxidation studies |
| CAS | 75899-68-2 |
| MW: | 156.2 D |
From 105.00€
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20-HETE
Item number: Cay90030-50
20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role in the renal and cerebral vasculature. In rat cerebral microvessels, 20-HETE is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction. 20-HETE is excreted mainly as the glucuronide conjugate. The...
| Keywords: | 20-hydroxy Arachidonic Acid, 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 79551-86-3 |
| MW: | 320.5 D |
From 217.00€
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Prostaglandin B1
Item number: Cay11110-1
Prostaglandin B1 (PGB1) is a non-enzymatic dehydration product of PGE1 resulting from treatment with strong base. Oligomers of PGB1 are known to exhibit antioxidant and ionophoric activity.Formal Name: 9-oxo-15S-hydroxy-prosta-8(12),13E-dien-1-oic acid. CAS Number: 13345-51-2. Synonyms: PGB1. Molecular Formula:...
| Keywords: | PGB1, 9-oxo-15S-hydroxy-prosta-8(12),13E-dien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 13345-51-2 |
| MW: | 336.5 D |
From 34.00€
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Arachidonic Acid (peroxide free)
Item number: Cay90010.1-100
Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient,...
| Keywords: | AA (peroxide free), 5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 506-32-1 |
| MW: | 304.5 D |
From 50.00€
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Leukotriene B4-d4
Item number: Cay320110-25
Leukotriene B4-d4 (LTB4-d4) is intended for use as an internal standard for the quantification of LTB4 (Cay-20110) by GC- or LC-MS. LTB4 is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion...
| Keywords: | LTB4-d4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic-6,7,14,15-d4 acid |
| Application: | Standard |
| CAS | 124629-74-9 |
| MW: | 340.5 D |
From 410.00€
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Thromboxane B2
Item number: Cay19030-1
Thromboxane B2 (TXB2) is a non-enzymatically derived, stable, inactive metabolite of TXA2, which is highly unstable. Serum levels of TXB2 positively correlate with platelet COX-1 activation. Urinary levels of TXB2 reflect intrarenal TXA2 synthesis, while its metabolites, 11-dehydro TXB2 (Cay-19500) and 2,3-dinor...
| Keywords: | TXB2, 9alpha,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 54397-85-2 |
| MW: | 370.5 D |
From 121.00€
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12(S)-HETE
Item number: Cay34570-25
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.Formal Name: 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid. CAS Number: 54397-83-0. Synonyms: 12(S)-Hydroxyeicosatetraenoic Acid....
| Keywords: | 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 54397-83-0 |
| MW: | 320.5 D |
From 189.00€
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