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Product information "9-deoxy-9-methylene Prostaglandin E2"
9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2 (Cay-14010). 9-deoxy-9-methylene PGE2 retains the biological profile of PGE2 with fewer side effects. In the rat 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in decreasing blood pressure. It also stimulates the gerbil colon and primate uterus at the same potency as PGE2.Formal Name: 11alpha,15S-dihydroxy-9-methylene-prosta-5Z,13E-dien-1-oic acid. CAS Number: 61263-32-9. Synonyms: 9-deoxy-9-methylene PGE2. Molecular Formula: C21H34O4. Formula Weight: 350.5. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: >100 mg/ml, DMSO: >100 mg/ml, Ethanol: >100 mg/ml, PBS (pH 7.2): >5 mg/ml. SMILES: O[C@H]1[C@H](/C=C/[C@@H](O)CCCCC)[C@@H](C/C=C\CCCC(O)=O)C(C1)=C. InChi Code: InChI=1S/C21H34O4/c1-3-4-7-10-17(22)13-14-19-18(16(2)15-20(19)23)11-8-5-6-9-12-21(24)25/h5,8,13-14,17-20,22-23H,2-4,6-7,9-12,15H2,1H3,(H,24,25)/b8-5-,14-13+/t17-,18-,19+,20+/m0/s1. InChi Key: VKEJXDXJUFQESA-DLMPNJEASA-N.
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