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Product information "8-iso-15-keto Prostaglandin E2"
8-iso-15-keto Prostaglandin E2 (8-iso-15-keto PGE2) is an isoprostane, one member of a large family of biomarkers produced by the free radical peroxidative degradation of membrane lipids. 8-iso-15-keto PGE2 is the theoretical first metabolite of 8-iso PGE2 via the 15-hydroxy PGDH pathway. While a number of potent biological activities have been attributed to 8-iso PGE2, there are no published reports at this time regarding its metabolism.Formal Name: (8beta)-11alpha-hydroxy-9,15-dioxo-prosta-5Z,13E-1-oic acid. CAS Number: 914804-63-0. Synonyms: 8-epi-15-keto PGE2, 8-iso-15-keto PGE2. Molecular Formula: C20H30O5. Formula Weight: 350.5. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: 33 mg/ml, DMSO: 20 mg/ml, Ethanol: 33 mg/ml, PBS (pH 7.2): 1.4 mg/ml. SMILES: CCCCCC(/C=C/[C@H]([C@@H]1C/C=C\CCCC(O)=O)[C@H](O)CC1=O)=O. InChi Code: InChI=1S/C20H30O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,16-17,19,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t16-,17+,19+/m0/s1. InChi Key: YRTJDWROBKPZNV-RSNVZYGJSA-N.
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