6alpha-Prostaglandin I1

6alpha-Prostaglandin I1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay18110-1 1 mg -

5 - 10 business days*

Cay18110-5 5 mg -

5 - 10 business days*

Cay18110-10 10 mg -

5 - 10 business days*

6alpha-Prostaglandin I1 (6alpha-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to... more
Product information "6alpha-Prostaglandin I1"
6alpha-Prostaglandin I1 (6alpha-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions. 6alpha-PGI1 promotes cyclic AMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the beta-isomer and 100-fold less potent than PGI2 in eliciting the response. 6alpha-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI2 (0.4 ng/ml). Formal Name: 6R,9alpha-epoxy-11alpha,15S-dihydroxy-prost-13E-en-1-oic acid. CAS Number: 62777-90-6. Synonyms: 6alpha-PGI1, 5,6alpha-dihydro PGI2. Molecular Formula: C20H34O5. Formula Weight: 354.5. Purity: >99%. Formulation: A crystalline solid. Solubility: DMF: >10 (from (6b-PGI1), DMSO: >5 (from (6b-PGI1), Ethanol: >20 mg/ml (from (6b-PGI1), PBS pH 7.2: >80 µg (from (6b-PGI1). SMILES: O[C@H]1[C@H](/C=C/[C@@H](O)CCCCC)[C@@H](C[C@](CCCCC(O)=O)([H])O2)[C@@H]2C1. InChi Code: InChI=1S/C20H34O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h10-11,14-19,21-22H,2-9,12-13H2,1H3,(H,23,24)/b11-10+/t14-,15+,16+,17+,18+,19-/m0/s1. InChi Key: RJADQDXZYFCVHV-WDONHGPHSA-N.
Keywords: 5,6alpha-dihydro PGI2, 6alpha-PGI1, 6R,9alpha-epoxy-11alpha,15S-dihydroxy-prost-13E-en-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 18110


Application: Bioactive lipid assays
MW: 354.5 D
Formula: C20H34O5
Purity: >99%
Format: Crystalline Solid

Database Information

CAS : 62777-90-6| Find alternatives

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Shipping: -20°C (International: -20°C)
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