5-iPF2alpha-VI-d11

5-iPF2alpha-VI-d11
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10006654-10 10 µg -

6 - 10 business days*

409.00€
Cay10006654-25 25 µg -

6 - 10 business days*

974.00€
 
(±)5-iPF2alpha-VI-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20,... more
Product information "5-iPF2alpha-VI-d11"
(±)5-iPF2alpha-VI-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of (±)5-iPF2alpha-VI (Cay-16300) by GC- or LC-mass spectrometry. Isoprostanes are prostaglandin-like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. iPF2alpha-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date, the most extensively studied of these is 8-isoprostane (8-epi-PGF2alpha, iPF2alpha-III). However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress, including iPF2alpha-VI of the type-VI isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones which facilitate their extraction and purification from biological samples. Formal Name: (±)5,9alpha,11alpha-trihydroxy-(8beta)-prosta-6E,14Z-dien-1-oic-16,16,17,17,18,18,19,19,20,20,20-d11 acid. CAS Number: 936565-17-2. Molecular Formula: C20H23D11O5. Formula Weight: 365.6. Purity: >99% deuterated forms (d1-d11). Formulation: A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: CCCCC/C=C\C[C@H]1C(O)CC(O)[C@H]1\C=C\C(O)CCCC(=O)O. InChi Code: InChI=1S/C20H34O5/c1-2-3-4-5-6-7-10-16-17(19(23)14-18(16)22)13-12-15(21)9-8-11-20(24)25/h6-7,12-13,15-19,21-23H,2-5,8-11,14H2,1H3,(H,24,25)/b7-6-,13-12+/t15?,16-,17+,18-,19+/m1/s1/i1D3,2D2,3D2,4D2,5D2. InChi Key: RZCPXIZGLPAGEV-AOORLBIGSA-N.
Keywords: (±)5,9alpha,11alpha-trihydroxy-(8beta)-prosta-6E,14Z-dien-1-oic-16,16,17,17,18,18,19,19,20,20,20-d11 acid
Supplier: Cayman Chemical
Supplier-Nr: 10006654

Properties

Application: Standard
MW: 365.6 D
Formula: C20H23D11O5
Purity: >99% deuterated forms (d1-d11)
Format: Solution

Database Information

CAS : 936565-17-2| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H360
P Phrases: P201, P202, P210, P233, P240, P241, P242, P243, P280, P303+361+353, P308+313, P370+378, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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