5-cis-15(R)-Iloprost

5-cis-15(R)-Iloprost is the C-5 cis-isomer and 15(R)-epimer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin. There are no published studies of the pharmacological properties of 5-cis-15(R)-iloprost. Formal Name: 6,9alpha-methylene-11alpha,15R-dihydroxy-16-methyl-prosta-5Z,13E-dien-18-yn-1-oic acid. Synonyms: 5-cis-15(R)-Ciloprost. Molecular Formula: C22H32O4. Formula Weight: 360.5. Purity: >97%. Formulation: A solution in methyl acetate. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O[C@@H]1C[C@H]2[C@H](C/C(C2)=C\CCCC(O)=O)[C@H]1/C=C/[C@H](O)C(C)CC#CC. InChi Code: InChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8-/t15?,17-,18+,19-,20-,21+/m0/s1. InChi Key: HIFJCPQKFCZDDL-KESZHIOGSA-N.