5,6-dehydro Arachidonic Acid

5,6-dehydro Arachidonic acid is an analog of arachidonic acid with an acetylene in the 5,6 position. It inhibits 5-LO in rat basophilic leukemia cells, with a Ki value of 15 µM. In guinea pig leukocytes, 5-LO is inhibited by 5,6-dehydro arachidonic acid with an IC50 value of 10 µM. Formal Name: 8Z,11Z,14Z-eicosatrien-5-ynoic acid. CAS Number: 58688-54-3. Synonyms: 5,6-dehydro AA. Molecular Formula: C20H30O2. Formula Weight: 302.5. Purity: >98%. Formulation: A solution in ethanol. Solubility: 0.15 M Tris-HCl pH 8.5: >1 mg/ml (from Oleic Acid), DMF: >100 mg/ml (from Oleic Acid), DMSO: >100 mg/ml (from Oleic Acid), Ethanol: >100 mg/ml (from Oleic Acid), PBS pH 7.2: <100 µg/ml (from Oleic Acid). SMILES: CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O. InChi Code: InChI=1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-. InChi Key: GIOQWSLKUVKKAO-QNEBEIHSSA-N.