2-O-methyl PAF C-18 (hydrate)

2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart. In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase.Formal Name: 4-hydroxy-7R-methoxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptacosan-1-aminium, inner salt, 4-oxide, hydrate. Synonyms: Edelfosine, ET-18-OCH3, 1-O-octadecyl-2-O-methyl-sn-glyceryl-3-phosphorylcholine. Molecular Formula: C27H58NO6P . XH2O. Formula Weight: 523.7. Purity: >98%. Formulation: (Request formulation change), A lyophilized powder. Solubility: PBS pH 7.2: 1 mg/ml. SMILES: CCCCCCCCCCCCCCCCCCOC[C@@H](OC)COP(OCC[N+](C)(C)C)([O-])=O.O. InChi Code: InChI=1S/C27H58NO6P.H2O/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-32-25-27(31-5)26-34-35(29,30)33-24-22-28(2,3)4,/h27H,6-26H2,1-5H3,1H2. InChi Key: FPHUJKAXWVAHPW-UHFFFAOYSA-N.