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Statistics & Tracking
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2-O-methyl-PAF C-18 is a synthetic PAF analog which contains a methyl group, attached by an ether linkage, at the sn-2 position. It has been shown to mediate a number of biological responses including decreasing plasma membrane fluidity and inhibiting tumor cell invasiveness in embryonic chick heart. In rat astrocytes, 2-O-methyl PAF C-18 causes the release of large quantities of nitric oxide by a pathway involving activation of nitric oxide synthase. Formal Name: 3,5,9-trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7R-methoxy-N,N,N-trimethyl-4-oxide. CAS Number: 77286-66-9. Synonyms: Edelfosine, ET-18-OCH3, 1-O-octadecyl-2-O-methyl-sn-glyceryl-3-phosphorylcholine. Molecular Formula: C27H58NO6P. Formula Weight: 523.7. Purity: >98%. Formulation: A lyophilized powder. Solubility: PBS pH 7.2: >4.5 mg/ml (from Lyso-PAF C-18. SMILES: CCCCCCCCCCCCCCCCCCOC[C@@H](OC)COP(OCC[N+](C)(C)C)([O-])=O. InChi Code: InChI=1S/C27H58NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-32-25-27(31-5)26-34-35(29,30)33-24-22-28(2,3)4/h27H,6-26H2,1-5H3. InChi Key: MHFRGQHAERHWKZ-UHFFFAOYSA-N.