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Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and... more
Product information "2,3-dinor Thromboxane B1"
Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. In rats and rabbits, 2,3-dinor TXB1 has been identified as another urinary metabolite of TXB2. However in human urine, only trace amounts of 2,3-dinor TXB1 have been identified. In rats, 2,3-dinor TXB1 is excreted at a much higher rate than 2,3-dinor TXB2 (19.2 ± 4.9 ng/24 hr and 1.6 ± 0.3 ng/24 hr, respectively). Therefore, urinary 2,3-dinor TXB1 is a suitable marker of thromboxane biosynthesis in rats. Formal Name: 9alpha,11,15S-trihydroxy-2,3-dinor-thromba-13E-en-1-oic acid. CAS Number: 196493-76-2. Synonyms: 2,3-dinor TXB1. Molecular Formula: C18H32O6. Formula Weight: 344.4. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 20 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): .15 mg/ml. SMILES: O[C@@H]1[C@H](CCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)OC(O)C1. InChi Code: InChI=1S/C18H32O6/c1-2-3-4-7-13(19)10-11-16-14(8-5-6-9-17(21)22)15(20)12-18(23)24-16/h10-11,13-16,18-20,23H,2-9,12H2,1H3,(H,21,22)/b11-10+/t13-,14-,15-,16+,18?/m0/s1. InChi Key: LGWCOUWMTAQMQT-QCBHMXSDSA-N.
Keywords: | 2,3-dinor TXB1, 9alpha,11,15S-trihydroxy-2,3-dinor-thromba-13E-en-1-oic acid |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10006330 |
Properties
Application: | Bioactive lipid assays |
MW: | 344.4 D |
Formula: | C18H32O6 |
Purity: | >98% |
Format: | Solution |
Database Information
CAS : | 196493-76-2| Find alternatives |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: | ![]() ![]() |
H Phrases: | EUH066, H225, H319, H336 |
P Phrases: | , P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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