17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2alpha

17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2alpha
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16895-1 1 mg -

6 - 10 business days*

Cay16895-5 5 mg -

6 - 10 business days*

Cay16895-10 10 mg -

6 - 10 business days*

A number of 17-phenyl trinor prostaglandin F2alpha (17-phenyl trinor PGF2alpha) derivatives have... more
Product information "17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2alpha"
A number of 17-phenyl trinor prostaglandin F2alpha (17-phenyl trinor PGF2alpha) derivatives have been approved for the treatment of glaucoma. Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects. 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2alpha bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2alpha would act very much like the free acid of latanoprost. Formal Name: 9alpha,11alpha,15R-trihydroxy-17-(3-(trifluoromethyl)phenyl)-18,19,20-trinor-prosta-5Z-en-1-oic acid. CAS Number: 294856-01-2. Synonyms: 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2alpha. Molecular Formula: C24H33O5F3. Formula Weight: 458.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](CC[C@@H](O)CCC2=CC(C(F)(F)F)=CC=C2)[C@H](O)C1. InChi Code: InChI=1S/C24H33F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h1,3,5-7,14,18-22,28-30H,2,4,8-13,15H2,(H,31,32)/b3-1-/t18-,19+,20+,21-,22+/m0/s1. InChi Key: GGAGMUSEFHEEBF-XPRPYWGDSA-N.
Keywords: 17-trifluoromethylphenyl-13,14-dihydro trinor PGF2alpha, 9alpha,11alpha,15R-trihydroxy-17-(3-(trifluoromethyl)phenyl)-18,19,20-trinor-prosta-5Z-en-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 16895


Application: Bioactive lipid assays
MW: 458.5 D
Formula: C24H33O5F3
Purity: >98%
Format: Solution

Database Information

CAS : 294856-01-2| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336, H360
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
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