17-phenyl trinor Prostaglandin F2alpha ethyl amide

17-phenyl trinor Prostaglandin F2alpha ethyl amide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16820-1 1 mg -

3 - 10 business days*

57.00€
Cay16820-5 5 mg -

3 - 10 business days*

254.00€
Cay16820-10 10 mg -

3 - 10 business days*

367.00€
Cay16820-50 50 mg -

3 - 10 business days*

914.00€
 
17-phenyl trinor Prostaglandin F2alpha ethyl amide (17-phenyl trinor PGF2alpha ethyl amide) is an... more
Product information "17-phenyl trinor Prostaglandin F2alpha ethyl amide"
17-phenyl trinor Prostaglandin F2alpha ethyl amide (17-phenyl trinor PGF2alpha ethyl amide) is an F-series PG analog which has been approved for use as an ocular hypotensive drug. Investigations in our lab have shown that 17-phenyl trinor PGF2alpha ethyl amide is converted by an amidase enzymatic activity in the bovine and human cornea to yield the corresponding free acid, with a conversion rate of about 40 µg/g corneal tissue/24 hours. The free acid, 17-phenyl trinor PGF2alpha, is a potent FP receptor agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. Formal Name: N-ethyl-9alpha,11alpha,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide. CAS Number: 155206-00-1. Synonyms: Bimatoprost, 15(S)-Bimatoprost, 17-phenyl trinor PGF2alpha ethyl amide. Molecular Formula: C25H37NO4. Formula Weight: 415.6. Purity: >97%. Formulation: A crystalline solid. Solubility: Acetonitrile: 3 mg/ml, DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 300 µg/ml. SMILES: CCN([H])C(CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C[C@@H]1O)=O. InChi Code: InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1. InChi Key: AQOKCDNYWBIDND-FTOWTWDKSA-N.
Keywords: 15(S)-Bimatoprost, 17-phenyl trinor PGF2alpha ethyl amide, Bimatoprost, N-ethyl-9alpha,11alpha,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-amide
Supplier: Cayman Chemical
Supplier-Nr: 16820

Properties

Application: Bioactive lipid assays
MW: 415.6 D
Formula: C25H37NO4
Purity: >97%
Format: Crystalline Solid

Database Information

CAS : 155206-00-1| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H302, H360
P Phrases: P201, P202, P264, P270, P280, P301+310, P308+313, P330, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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