17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

Docosapentaenoic acid (DPA) is a omega-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARgamma agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 µM).Formal Name: 7Z,10Z,13Z,15E,19Z-17-oxo-docosapentaenoic acid. CAS Number: 1233715-33-7. Synonyms: EFOX, 17-oxo-DPA, 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-DPA. Molecular Formula: C22H32O3. Formula Weight: 344.5. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 15 mg/ml, DMSO: 10 mg/ml, Ethanol: 20 mg/ml. lambdamax: 282 nm. SMILES: CC/C=C\CC(=O)/C=C\C=C\C/C=C\C/C=C\CCCCCC(=O)O. InChi Code: InChI=1S/C22H32O3/c1-2-3-15-18-21(23)19-16-13-11-9-7-5-4-6-8-10-12-14-17-20-22(24)25/h3,5-8,11,13,15-16,19H,2,4,9-10,12,14,17-18,20H2,1H3,(H,24,25)/b7-5-,8-6-,13-11-,15-3-,19-16+. InChi Key: PWVSFTLICCBISU-UCMLWGQMSA-N.