16(R)-Iloprost

16(R)-Iloprost
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13076-500 500 µg -

6 - 10 business days*

153.00€
Cay13076-1 1 mg -

6 - 10 business days*

290.00€
Cay13076-5 5 mg -

6 - 10 business days*

1,220.00€
 
Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold... more
Product information "16(R)-Iloprost"
Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the recombinant human IP and EP1 receptors with a Ki value of 11 nM. Most preparations of iloprost contain 16(S) and 16(R) stereoisomers. 16(R)-Iloprost inhibits platelet aggregation with an IC50 value of 65 nM. Formal Name: 6,9alpha-methylene-11alpha,15S-dihydroxy-16R-methyl-prosta-5E,13E-dien-18-yn-1-oic acid. CAS Number: 74843-13-3. Molecular Formula: C22H32O4. Formula Weight: 360.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O[C@@H]1C[C@H](C/2)[C@H](CC2=C\CCCC(O)=O)[C@H]1/C=C/[C@@H](O)[C@H](C)CC#CC. InChi Code: InChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8+/t15-,17+,18-,19+,20-,21-/m1/s1. InChi Key: HIFJCPQKFCZDDL-GBSCXWAGSA-N.
Keywords: 6,9alpha-methylene-11alpha,15S-dihydroxy-16R-methyl-prosta-5E,13E-dien-18-yn-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 13076

Properties

Application: PGI2 analog
MW: 360.5 D
Formula: C22H32O4
Purity: >98%
Format: Solution

Database Information

CAS : 74843-13-3| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H301, H311, H319, H331, H336, H361
P Phrases: P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+310, P302+352, P303+361+353, P304+340, P305+351+338, P308+313, P311, P312, P321, P330, P337+313, P361+364, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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