(±)16-HETE

(±)16-HETE
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010635-25 25 µg -

6 - 10 business days*

150.00€
Cay10010635-50 50 µg -

6 - 10 business days*

285.00€
Cay10010635-100 100 µg -

6 - 10 business days*

540.00€
 
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its... more
Product information "(±)16-HETE"
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)16-HETE is the racemic version of a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation. The biological activity of 16-HETE is stereospecific. 16(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, however 16(S)-HETE does not affect perfusion pressure. At a concentration of 2 µM the (S)-enantiomer of 16-HETE inhibits proximal tubule ATPase activity by as much as 60%, whereas the (R)-isomer has negligible effects on ATPase activity. Formal Name: (±)16-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid. CAS Number: 128914-46-5. Molecular Formula: C20H32O3. Formula Weight: 320.5. Purity: >98%. Formulation: A solution in ethanol. Solubility: 0.1 M Na2CO3: 2 mg/ml, DMF: Miscible, DMSO: Miscible, Ethanol: Miscible, PBS (pH 7.2): 0.8 mg/ml. SMILES: CCCCC(O)/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O. InChi Code: InChI=1S/C20H32O3/c1-2-3-16-19(21)17-14-12-10-8-6-4-5-7-9-11-13-15-18-20(22)23/h4-5,8-11,14,17,19,21H,2-3,6-7,12-13,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,17-14-. InChi Key: JEKNPVYFNMZRJG-UFINWASNSA-N.
Keywords: (±)16-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Supplier: Cayman Chemical
Supplier-Nr: 10010635

Properties

Application: Bioactive lipid assays
MW: 320.5 D
Formula: C20H32O3
Purity: >98%
Format: Solution

Database Information

CAS : 128914-46-5| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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