15(S)-HpEPE

15(S)-HpEPE is an active metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed from EPA by 15-lipoxygenase (15-LO). 15(S)-HpEPE (0.01, 0.3, and 1 µM) inhibits IL-1beta-induced increases in the levels of COX-2 in human pulmonary microvascular endothelial cells (HPMECs).Formal Name: 15S-hydroperoxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic acid. CAS Number: 125992-60-1. Molecular Formula: C20H30O4. Formula Weight: 334.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: 0.1 M Na2CO3: 2 mg/ml, DMF: Miscible, DMSO: Miscible, Ethanol: Miscible, PBS pH 7.2: 0.8 mg/ml. lambdamax: 236 nm. SMILES: CC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\C/C=C\CCCC(O)=O. InChi Code: InChI=1S/C20H30O4/c1-2-3-13-16-19(24-23)17-14-11-9-7-5-4-6-8-10-12-15-18-20(21)22/h3-5,8-11,13-14,17,19,23H,2,6-7,12,15-16,18H2,1H3,(H,21,22)/b5-4-,10-8-,11-9-,13-3-,17-14+. InChi Key: FPMFSFWYWZLDKP-XWJJKCKWSA-N.