15(R)-Prostaglandin F2alpha

15(R)-Prostaglandin F2alpha (15(R)-PGF2alpha) is the C-15 epimer of the naturally occurring mammalian autacoid PGF2alpha. It has only 25% of the potency of PGF2alpha in hamster antifertility studies, which may be due to reduced affinity for FP receptors. Compared to PGF2alpha, 15(R)-PGF2alpha has a binding affinity of 6.7% to ovine luteal cell receptors. Similarly, the binding affinity to rat vascular smooth muscle cells is negligible as compared to PGF2alpha.Formal Name: 9alpha,11alpha,15R-trihydroxy-prosta-5Z,13E-dien-1-oic acid. CAS Number: 37658-84-7. Synonyms: 15-epi PGF2alpha, 15(R)-PGF2alpha. Molecular Formula: C20H34O5. Formula Weight: 354.5. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: 10 mM Na2CO3: >6.5 mg/ml, DMF: >100 mg/ml, DMSO: >100 mg/ml, Ethanol: >100 mg/ml, PBS (pH 7.2): >10 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@H](O)CCCCC)[C@H](O)C1. InChi Code: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17-,18+,19-/m1/s1. InChi Key: PXGPLTODNUVGFL-CKXCCYAOSA-N.