15(R)-Prostaglandin D2

15(R)-Prostaglandin D2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10118-1 1 mg -

3 - 10 business days*

79.00€
Cay10118-5 5 mg -

3 - 10 business days*

374.00€
Cay10118-10 10 mg -

3 - 10 business days*

709.00€
 
Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane... more
Product information "15(R)-Prostaglandin D2"
Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane GPCR, the DP1 receptor. However, in certain leukocytes and other immune cells, a second PGD2 receptor referred to as the CRTH2 or DP2 receptor has been cloned and characterized. 15(R)-15-methyl PGD2 is a surprisingly potent agonist at the DP2 receptor, being about 5 times more potent than PGD2 itself. 15(R)-PGD2 has the potential to be produced endogenously as a natural ligand for DP2, unlike the synthetic 15-methyl analogs. In preliminary reports, 15(R)-PGD2 has also been reported to be a potent and selective DP2 receptor agonist.
Keywords: 15(R)-PGD2, 9alpha,15R-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 10118-1

Properties

Application: DP2 receptor agonist
MW: 352.5 D
Formula: C20H32O5
Purity: >98%
Format: Solution

Database Information

CAS : 59894-05-2| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336, EUH066
P Phrases: P210, P240, P241, P242, P243, P261, P264, P271, P280, P312, P303+P361+P353, P304+P340, P305+P351+P338, P337+P313, P370+P378, P405, P403+P233, P403+P235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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