15(R)-Prostaglandin D2

15(R)-Prostaglandin D2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10118-1 1 mg -

3 - 10 business days*

79.00€
Cay10118-5 5 mg -

3 - 10 business days*

374.00€
Cay10118-10 10 mg -

3 - 10 business days*

709.00€
 
Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane... more
Product information "15(R)-Prostaglandin D2"
Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane GPCR, the DP1 receptor. However, in certain leukocytes and other immune cells, a second PGD2 receptor referred to as the CRTH2 or DP2 receptor has been cloned and characterized. 15(R)-15-methyl PGD2 is a surprisingly potent agonist at the DP2 receptor, being about 5 times more potent than PGD2 itself. 15(R)-PGD2 has the potential to be produced endogenously as a natural ligand for DP2, unlike the synthetic 15-methyl analogs. In preliminary reports, 15(R)-PGD2 has also been reported to be a potent and selective DP2 receptor agonist. Formal Name: 9alpha,15R-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid. CAS Number: 59894-05-2. Synonyms: 15(R)-PGD2. Molecular Formula: C20H32O5. Formula Weight: 352.5. Purity: >98%. Formulation: A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.4): 1 mg/ml. SMILES: CCCCC[C@@H](O)/C=C/[C@H]1C(=O)CC(O)C1C/C=C\CCCC(=O)O. InChi Code: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17-,18+/m1/s1. InChi Key: BHMBVRSPMRCCGG-DFVNJMEGSA-N.
Keywords: 15(R)-PGD2, 9alpha,15R-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 10118

Properties

Application: DP2 receptor agonist
MW: 352.5 D
Formula: C20H32O5
Purity: >98%
Format: Solution

Database Information

CAS : 59894-05-2| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336
P Phrases: , P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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