15(R),19(R)-hydroxy Prostaglandin F2alpha

19(R)-Hydroxylated prostaglandins (PGs) occur in µg/ml concentrations in the semen of certain mammalian species, especially primates. In the case of humans, the compounds are primarily of the PGE series, and the hydroxyl stereochemistry is 15(S),19(R). 19(R)-Hydroxylated PGs are also found in the seminal plasma of marsupials, where F-type compounds of the 1 and 2-series predominate. The 15(R)-hydroxy epimer of these 19-hydroxylated PGs is the inverse or "unnatural" isomer at C-15. The biological role of 19(R)-hydroxylated PGs is not well established. In the F-series, 19(R)-hydroxylation is associated with a significant loss of receptor-mediated biological activity in some assays.Formal Name: 9alpha,11alpha,15R,19R-tetrahydroxy-prosta-5Z,13E-dien-1-oic acid. CAS Number: 1224444-23-8. Synonyms: 15(R),19(R)-hydroxy PGF2alpha. Molecular Formula: C20H34O6. Formula Weight: 370.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: >100 mg/ml, DMSO: >100 mg/ml, Ethanol: >100 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@H](O)CCC[C@H](O)C)[C@H](O)C1. InChi Code: InChI=1S/C20H34O6/c1-14(21)7-6-8-15(22)11-12-17-16(18(23)13-19(17)24)9-4-2-3-5-10-20(25)26/h2,4,11-12,14-19,21-24H,3,5-10,13H2,1H3,(H,25,26)/b4-2-,12-11+/t14-,15-,16-,17-,18+,19-/m1/s1. InChi Key: UBWZMPMLSDJDSU-ZYPCAQTJSA-N.