15(R),19(R)-hydroxy Prostaglandin E1

19(R)-Hydroxylated prostaglandins occur in µg/ml concentrations in the semen of certain mammalian species, especially primates. In the case of humans, the compounds are primarily of the PGE series, and the hydroxyl stereochemistry is 15(S),19(R). 19(R)-Hydroxylated prostaglandins are also found in the seminal plasma of marsupials, where F-type compounds of the 1 and 2-series predominate. The 15(R)-hydroxy epimer of these 19-hydroxylated prostaglandins is the inverse or "unnatural" isomer at C-15. The biological role of 19(R)-hydroxylated prostaglandins is not well established. In the E-series, 19(R)-hydroxylation has been identified with EP2 receptor subtype selectivity.Formal Name: 9-oxo-11alpha,15R,19R-trihydroxy-prost-13E-en-1-oic acid. Synonyms: 15(R),19(R)-hydroxy PGE1. Molecular Formula: C20H34O6. Formula Weight: 370.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: >100 mg/ml, DMSO: >50 mg/ml, Ethanol: >50 mg/ml, PBS (pH 7.2): >1.67 mg/ml. SMILES: O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](O)CCC[C@H](O)C)[C@H](O)C1. InChi Code: InChI=1S/C20H34O6/c1-14(21)7-6-8-15(22)11-12-17-16(18(23)13-19(17)24)9-4-2-3-5-10-20(25)26/h11-12,14-17,19,21-22,24H,2-10,13H2,1H3,(H,25,26)/b12-11+/t14-,15-,16-,17-,19-/m1/s1. InChi Key: QVVXWHIDRKRPMO-HESWFPMQSA-N.