15-keto Latanoprost (free acid)

15-keto Latanoprost (free acid)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16815-1 1 mg -

6 - 10 business days*

87.00€
Cay16815-5 5 mg -

6 - 10 business days*

389.00€
Cay16815-10 10 mg -

6 - 10 business days*

690.00€
 
15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals.... more
Product information "15-keto Latanoprost (free acid)"
15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-keto latanoprost still retains the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 µg/eye. 15-keto Latanoprost is also a miotic in the normal cat eye, causing an 8 mm Hg reduction in pupillary diameter at 5 µg/eye. Again, this is not as potent as many other F-type prostaglandins, for example, prostaglandin F2alpha will produce this degree of miosis at a dose of less than 1 µg/eye. Formal Name: 9alpha,11alpha-dihydroxy-15-oxo-17-phenyl-18,19,20-trinor-prost-5Z-en-1-oic acid. CAS Number: 369585-22-8. Molecular Formula: C23H32O5. Formula Weight: 388.5. Purity: >95%. Formulation: A solution in methyl acetate. Solubility: DMF: 50 mg/ml, DMSO: 33 mg/ml, DMSO:PBS (1:1): 500 µg/ml, Ethanol: 50 mg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](CCC(CCC2=CC=CC=C2)=O)[C@H](O)C1. InChi Code: InChI=1S/C23H32O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,19-22,25-26H,2,7,10-16H2,(H,27,28)/b6-1-/t19-,20-,21+,22-/m1/s1. InChi Key: OFISZERSIOETNK-LYTHEMCMSA-N.
Keywords: 9alpha,11alpha-dihydroxy-15-oxo-17-phenyl-18,19,20-trinor-prost-5Z-en-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 16815

Properties

Application: Bioactive lipid assays
MW: 388.5 D
Formula: C23H32O5
Purity: >95%
Format: Solution

Database Information

CAS : 369585-22-8| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336, H360
P Phrases: , P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P308+313, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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