15-deoxy-Delta12,14-Prostaglandin J2 MaxSpec(R) Standard

15-deoxy-Delta12,14-Prostaglandin J2 MaxSpec(R) Standard
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007235-100 100 µg -

5 - 10 business days*

69.00€
 
15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 (Cay-12010,... more
Product information "15-deoxy-Delta12,14-Prostaglandin J2 MaxSpec(R) Standard"
15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 (Cay-12010, Cay-10007202) by the elimination of two molecules of water. It binds selectively to PPARgamma with an EC50 value of 2 µM in a murine chimera system. 15-deoxy-Delta12,14-PGJ2 is more potent than PGD2, Delta12-PGJ2 (Cay-18550, Cay-10007234), and PGJ2 (Cay-18500, Cay-10007233) in stimulating lipogenesis in C3H10T1/2 cells. The EC50 value for induction of adipocyte differentiation in cultured fibroblasts is 7 µM. 15-deoxy-Delta12,14-PGJ2 MaxSpec(R) standard is a quantitative grade standard of 15-deoxy-Delta12,14-PGJ2 (Cay-18570) that has been prepared specifically for mass spectrometry or any application where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. This 15-deoxy-Delta12,14-PGJ2 MaxSpec(R) standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality. Formal Name: 11-oxo-prosta-5Z,9,12E,14Z-tetraen-1-oic acid. CAS Number: 87893-55-8. Synonyms: 15-deoxy-Delta12,14-PGJ2. Molecular Formula: C20H28O3. Formula Weight: 316.4. Purity: >95%. Formulation: A solution in methyl acetate at 100 µg/ml. SMILES: CCCCC/C=C/C=C1C(C=C[C@@H]/1C/C=C\CCCC(O)=O)=O. InChi Code: InChI=1S/C20H28O3/c1-2-3-4-5-6-10-13-18-17(15-16-19(18)21)12-9-7-8-11-14-20(22)23/h6-7,9-10,13,15-17H,2-5,8,11-12,14H2,1H3,(H,22,23)/b9-7-,10-6+,18-13+/t17-/m0/s1. InChi Key: VHRUMKCAEVRUBK-GODQJPCRSA-N.
Keywords: 15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14Z-tetraen-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 10007235

Properties

Application: Bioactive lipid assays
MW: 316.4 D
Formula: C20H28O3
Purity: >95%
Format: Solution

Database Information

CAS : 87893-55-8| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336
P Phrases: P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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