15-deoxy-Delta12,14-Prostaglandin J2

15-deoxy-Delta12,14-Prostaglandin J2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay18570-100 100 µg -

6 - 10 business days*

Cay18570-500 500 µg -

6 - 10 business days*

Cay18570-1 1 mg -

approx. 1-3 business days

Cay18570-5 5 mg -

6 - 10 business days*

15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 by the... more
Product information "15-deoxy-Delta12,14-Prostaglandin J2"
15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARgamma with an EC50 value of 2 µM in a murine chimera system. 15-deoxy-Delta12,14-PGJ2 is more potent than PGD2, Delta12-PGJ2, and PGJ2 in stimulating lipogenesis in C3H10T1/2 cells. The EC50 for induction of adipocyte differentiation in cultured fibroblasts is 7 µM. Formal Name: 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid. CAS Number: 87893-55-8. Synonyms: 15-deoxy-Delta12,14-PGJ2. Molecular Formula: C20H28O3. Formula Weight: 316.4. Purity: >95%. Formulation: A solution in methyl acetate. Solubility: DMF: >100 mg/ml (from PGD2), DMSO: >20 mg/ml, Ethanol: >75 mg/ml (from PGD2), PBS pH 7.2: 2 mg/ml. lambdamax: 229, 306 nm. SMILES: O=C1/C([C@@H](C/C=C\CCCC(O)=O)C=C1)=C/C=C/CCCCC. InChi Code: InChI=1S/C20H28O3/c1-2-3-4-5-6-10-13-18-17(15-16-19(18)21)12-9-7-8-11-14-20(22)23/h6-7,9-10,13,15-17H,2-5,8,11-12,14H2,1H3,(H,22,23)/b9-7-,10-6+,18-13+/t17-/m0/s1. InChi Key: VHRUMKCAEVRUBK-GODQJPCRSA-N.
Keywords: 15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid
Supplier: Cayman Chemical
Supplier-Nr: 18570


Application: Bioactive lipid assays
MW: 316.4 D
Formula: C20H28O3
Purity: >95%
Format: Solution

Database Information

CAS : 87893-55-8| Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: EUH066, H225, H319, H336
P Phrases: , P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+361+353, P304+340, P305+351+338, P312, P337+313, P370+378, P403+233, P403+235, P405, P501
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