13,14-dihydro-15-keto Prostaglandin A2

PGE2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2, which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin. Further decomposition of 13,14-dihydro-15-keto PGA2 by the intentional addition of base produces bicyclo PGE2, a stable marker of PGE2 biosynthesis.Formal Name: 9,15-dioxo-prosta-5Z,10-dien-1-oic acid. CAS Number: 74872-89-2. Synonyms: 13,14-dihydro-15-keto PGA2. Molecular Formula: C20H30O4. Formula Weight: 334.5. Purity: >98%. Formulation: (Request formulation change), A solution in methyl acetate. Solubility: DMF: >75 mg/ml, DMSO: >50 mg/ml, Ethanol: >100 mg/ml, PBS (pH 7.2): >2.4 mg/ml. lambdamax: 216 nm. SMILES: O=C1[C@H](C/C=C\CCCC(O)=O)[C@@H](CCC(CCCCC)=O)C=C1. InChi Code: InChI=1S/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,13,15-16,18H,2-3,5-6,8-12,14H2,1H3,(H,23,24)/b7-4-/t16-,18+/m0/s1. InChi Key: FMKLAIBZMCURLI-BFVRRIQPSA-N.