13,14-dehydro-15-cyclohexyl Carbaprostacyclin

13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2. It inhibits the ADP-induced aggregation of human platelets with an ED50 of about 40 nM in PRP and 77 nM in washed platelets, which is comparable to the potency of carbaprostacyclin.Formal Name: [3aS-(2E,3aalpha,4alpha,5beta,6aalpha)]-5-[hexahydro-5-hydroxy-4-[(1-hydroxycyclohexyl)ethynyl]-2(1H)-pentalenylidene]-pentanoic acid. CAS Number: 145375-81-1. Molecular Formula: C21H30O4. Formula Weight: 346.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: >10 mg/ml, DMSO: >5 mg/ml, Ethanol: >20 mg/ml, PBS (pH 7.2): >80 mg/ml. SMILES: OC1(C#C[C@H]2[C@H](O)C[C@H]3[C@@H]2C/C(C3)=C/CCCC(O)=O)CCCCC1. InChi Code: InChI=1S/C21H30O4/c22-19-14-16-12-15(6-2-3-7-20(23)24)13-18(16)17(19)8-11-21(25)9-4-1-5-10-21/h6,16-19,22,25H,1-5,7,9-10,12-14H2,(H,23,24)/b15-6+/t16-,17+,18-,19+/m0/s1. InChi Key: LGIPMFCHTFFLFR-PRYZLTTQSA-N.