11-trans Leukotriene D4

11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.Formal Name: 5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E,14Z-eicosatetraenoic acid. CAS Number: 79768-40-4. Synonyms: 11-trans LTD4. Molecular Formula: C25H40N2O6S. Formula Weight: 496.7. Purity: >97%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 0.1 mg/ml. lambdamax: 278 nm. SMILES: CCCCC/C=C\C/C=C/C=C/C=C/[C@@H](SC[C@H](N)C(NCC(O)=O)=O)[C@@H](O)CCCC(O)=O. InChi Code: InChI=1S/C25H40N2O6S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22(21(28)15-14-17-23(29)30)34-19-20(26)25(33)27-18-24(31)32/h6-7,9-13,16,20-22,28H,2-5,8,14-15,17-19,26H2,1H3,(H,27,33)(H,29,30)(H,31,32)/b7-6-,10-9+,12-11+,16-13+/t20?,21-,22+/m0/s1. InChi Key: YEESKJGWJFYOOK-XILINCIBSA-N.