11-trans Leukotriene C4

11-trans Leukotriene C4
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay20230-25 25 µg -

3 - 10 business days*

Cay20230-50 50 µg -

3 - 10 business days*

Cay20230-100 100 µg -

3 - 10 business days*

11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. LTC4 undergoes slow... more
Product information "11-trans Leukotriene C4"
11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative to LTC4 in ionophore-stimulated HMC-1 cells (a human mast cell line) and equine eosinophils, but not in human neutrophils or RBL-1 cells. It is nearly equipotent with LTC4 for contraction of guinea pig parenchymal and ileum. In a radioligand binding assay using guinea pig ileum as a cysteinyl leukotriene receptor preparation, the pKis for LTC4 and 11-trans LTC4 were determined to be 6.42 and 6.58, respectively. Formal Name: 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11E,14Z-eicosatetraenoic acid. CAS Number: 74841-69-3. Synonyms: 11-trans LTC4. Molecular Formula: C30H47N3O9S. Formula Weight: 625.8. Purity: >97%. Formulation: A solution in ethanol. Solubility: DMF: >50 mg/ml (per Ramki Iyer), DMSO: >50 mg/ml (per Ramki Iyer), Ethanol: >50 mg/ml (per Ramki Iyer), PBS pH 7.2: >100 µg/ml (per Ramki Iyer). lambdamax: 280 nm. SMILES: CCCCC/C=C\C/C=C/C=C/C=C/[C@@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)[C@@H](O)CCCC(O)=O. InChi Code: InChI=1S/C30H47N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h6-7,9-13,16,22-25,34H,2-5,8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b7-6-,10-9+,. InChi Key: GWNVDXQDILPJIG-GXMXCQGXSA-N.
Keywords: 11-trans LTC4, 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11E,14Z-eicosatetraenoic acid
Supplier: Cayman Chemical
Supplier-Nr: 20230


Application: Bioactive lipid assays
MW: 625.8 D
Formula: C30H47N3O9S
Purity: >97%
Format: Solution

Database Information

CAS : 74841-69-3| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
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