11(12)-EET Ethanolamide

11(12)-EET Ethanolamide
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008598-25 25 µg -

5 - 10 business days*

90.00€
Cay10008598-50 50 µg -

5 - 10 business days*

172.00€
Cay10008598-100 100 µg -

5 - 10 business days*

324.00€
 
Arachidonoyl ethanolamide (AEA, anandamide) is an endogenous lipid neurotransmitter with... more
Product information "11(12)-EET Ethanolamide"
Arachidonoyl ethanolamide (AEA, anandamide) is an endogenous lipid neurotransmitter with cannibingeric activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. Fatty acid amide hydrolase (FAAH) is the enzyme responsible for the hydrolysis and inactivation of AEA. Metabolism of AEA by cyclooxygenase-2, leading to formation of prostaglandin ethanolamides, and by lipoxygenases has also been documented. (±)11(12)-EET ethanolamide is a potential cytochrome P450 (CYP450) metabolite of AEA, although specific stereochemistry rather than a racemic mixture would likely ensue from enzymatic metabolism. CYP450 metabolism of AEA may be particularly relevant under conditions of FAAH inhibition. Evidence for the formation of (±)11(12)-EET ethanolamide in vivo has not been documented. Formal Name: N-(2-hydroxyethyl)-(±)11(12)-epoxy-5Z,8Z,14Z-eicosatrienamide. Synonyms: (±)11,12-EpETrE Ethanolamide. Molecular Formula: C22H37NO3. Formula Weight: 363.5. Purity: >98%. Formulation: A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 20 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml. SMILES: CCCCC/C=C\C[C@H]1O[C@H]1C/C=C\C/C=C\CCCC(=O)NCCO. InChi Code: InChI=1S/C22H37NO3/c1-2-3-4-5-9-12-15-20-21(26-20)16-13-10-7-6-8-11-14-17-22(25)23-18-19-24/h6,8-10,12-13,20-21,24H,2-5,7,11,14-19H2,1H3,(H,23,25)/b8-6-,12-9-,13-10-/t20-,21+/m1/s1. InChi Key: TYRRSRADDAROSO-ABRALVTRSA-N.
Keywords: (±)11,12-EpETrE Ethanolamide, N-(2-hydroxyethyl)-(±)11(12)-epoxy-5Z,8Z,14Z-eicosatrienamide
Supplier: Cayman Chemical
Supplier-Nr: 10008598

Properties

Application: Bioactive lipid assays
MW: 363.5 D
Formula: C22H37NO3
Purity: >98%
Format: Solution

Database Information

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225
P Phrases: P210, P233, P240, P241, P242, P243, P280, P303+361+353, P370+378, P403+235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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