1-Stearoyl-2-Arachidonoyl-sn-Glycerol-d8

1-Stearoyl-2-Arachidonoyl-sn-Glycerol-d8
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10009872-100 100 µg -

3 - 10 business days*

57.00€
Cay10009872-500 500 µg -

3 - 10 business days*

254.00€
Cay10009872-1 1 mg -

3 - 10 business days*

450.00€
 
1-Stearoyl-2-arachidonoyl-d8-sn-glycerol (SAG-d8) is intended for use as an internal standard for... more
Product information "1-Stearoyl-2-Arachidonoyl-sn-Glycerol-d8"
1-Stearoyl-2-arachidonoyl-d8-sn-glycerol (SAG-d8) is intended for use as an internal standard for the quantification of SAG (Cay-10008650) by GC- or LC-MS. Many protein kinase C (PKC) isoforms require activation via second messengers including Ca2+, diacylglycerol (DAG), and/or a phospholipid in order to phosphorylate target proteins, initiating a variety of important signaling cascades. 1-Stearoyl-2-arachidonoyl-sn-glycerol (SAG) is a DAG that contains the omega-6 polyunsaturated fatty acid arachidonic acid in the sn-2 position and stearic acid in the sn-1 position of the glycerol backbone. It can potently activate PKCalpha, epsilon, and delta at nM concentrations. Independent of PKC signaling, SAG competitively binds to the Ras activator RasGRP with a Ki value of 4.49 µM in Jurkat T cells.
Keywords: SAG-d8, 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-5,6,8,9,11,12,14,15-d8-sn-glycerol
Supplier: Cayman Chemical
Supplier-Nr: 10009872-100

Properties

Application: Standard
MW: 653.1 D
Formula: C41H64D8O5
Purity: >99% deuterated forms (d1-d8)
Format: Solution

Database Information

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H302, H312, H319, H332
P Phrases: P210, P233, P240, P241, P242, P243, P264, P280, P303+P361+P353, P305+P351+P338, P337+P313, P370+P378, P403+P235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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