1-Stearoyl-2-Arachidonoyl-sn-Glycerol

1-Stearoyl-2-Arachidonoyl-sn-Glycerol
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10008650-5 5 mg -

3 - 10 business days

50.00€
Cay10008650-10 10 mg -

3 - 10 business days

90.00€
Cay10008650-25 25 mg -

3 - 10 business days

203.00€
 
Many protein kinase C (PKC) isoforms require activation via second messengers including Ca2+,... more
Product information "1-Stearoyl-2-Arachidonoyl-sn-Glycerol"
Many protein kinase C (PKC) isoforms require activation via second messengers including Ca2+, diacylglycerol (DAG), and/or a phospholipid to phosphorylate target proteins and they initiate a variety of important signalling cascades. 1-Stearoyl-2-arachidonoyl-sn-glycerol (SAG) is a DAG that contains the omega-6 polyunsaturated fatty acid arachidonic acid in the sn-2 position and stearic acid in the sn-1 position of the glycerol backbone. It can potently activate PKCalpha, PKCepsilon, and PKCdelta at nM concentrations. Independent of PKC signalling, SAG competitively binds to the Ras activator RasGRP with a Ki value of 4.49 µM in Jurkat T-cells.
Keywords: SAG, 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol
Supplier: Cayman Chemical
Supplier-Nr: 10008650-5

Properties

Application: Bioactive lipid assays
MW: 645 D
Formula: C41H72O5
Purity: >95%
Format: Solution

Database Information

CAS : 65914-84-3| Find alternatives

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H319, H336, EUH066
P Phrases: P210, P240, P241, P242, P243, P261, P264, P271, P280, P312, P303+P361+P353, P304+P340, P305+P351+P338, P337+P313, P370+P378, P405, P403+P233, P403+P235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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