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Product information "1-Palmitoyl Lysophosphatidic Acid (sodium salt)"
1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of five different G protein-coupled receptors (GPCRs) to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. In addition to playing a role in the aforementioned biological responses, 1-palmitoyl LPA enhances the action of beta-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of Pseudomonas aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+. Formal Name: 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate, monosodium salt. CAS Number: 17618-08-5. Synonyms: 1-Palmitoyl LPA. Molecular Formula: C19H38O7P . Na. Formula Weight: 432.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: <.05 mg/ml, DMSO: <.05 mg/ml, Ethanol: <.05 mg/ml. SMILES: CCCCCCCCCCCCCCCC(OC[C@@H](O)COP([O-])(O)=O)=O.[Na+]. InChi Code: InChI=1S/C19H39O7P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24,/h18,20H,2-17H2,1H3,(H2,22,23,24),/q,+1/p-1/t18-,/m1./s1. InChi Key: NWOPIWLNGYLZCJ-GMUIIQOCSA-M. Side Chain Carbon Sum: 16:0.
1-Palmitoyl LPA, 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate, monosodium salt