Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABD-21261 | 1 mg | - |
3 - 8 business days* |
279.00€
|
Zinquin AM ester is a lipophilic, zinc-sensitive, cell-permeable fluorescent probe. It is... more
Product information "Zinquin AM *UltraPure grade*"
Zinquin AM ester is a lipophilic, zinc-sensitive, cell-permeable fluorescent probe. It is retained in living cells because the AM ester is cleaved by cytosolic esterase to give Zinquin that carry a negative charge, preventing its efflux across the plasma membrane. Zinquin fluorescent probes may be loaded into cells by in the culture medium containing 5-40 ?M Zinquin ethyl ester in PBS with calcium and magnesium (or in culture medium). Cells are normally incubated with the Zinquin ethyl ester for 15-30 minutes at 37 °C. Exact loading concentration, time and temperature depend on the purpose of the experiment and cell type, and so will need to be optimized experimentally. Cells are washed in PBS with culture medium to remove extracellular remaining dye. Cells are observed under microscope or used for confocal microscopy, FACS or spectrofluorimetry analysis. Zinc is the second most abundant transition metal in the body and it is essential as catalytic, structural and regulatory ion. Zinc ions are involved in homeostasis, immune responses, oxidative stress, apoptosis and aging. Zinc has been proposed to function as a conventional neurotransmitter for the presynaptic neuron and as a transmembrane signal to traverse the postsynaptic neuron. Aberrant zinc metabolism is associated with many neurological diseases including Alzheimers disease, Parkinsons disease and epilepsy. The most suitable technique for in vivo monitoring of zinc has been proven to be fluorescence imaging.
Supplier: | AAT Bioquest |
Supplier-Nr: | 21261 |
Properties
Application: | Zinc monitoring |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Signal Word: | Warning |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed