Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABD-21211 | 1 mg | - |
3 - 8 business days* |
279.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Ex: 384 nm. Em: 540 nm. Soluble in: Water. The existing pH probes are ill-adapted to study acidic... more
Product information "RatioWorks(TM) PDMPO Dextran"
Ex: 384 nm. Em: 540 nm. Soluble in: Water. The existing pH probes are ill-adapted to study acidic organelles such as lysosomes, endosomes, phagosomes, spermatozoa and acrosomes because their fluorescence is significantly reduced at lower pH. The growing potential of ratio imaging is significantly limited by the lack of appropriate fluorescent probes for acidic organelles although ratio imaging has received intensive attention in the past few decades. RatioWorksT PDMPO is characterized as acidotropic dual-excitation and dual-emission pH probe. It emits intense yellow fluorescence at lower pH and gives intense blue fluorescence at higher pH. This unique pH-dependent fluorescence makes RatioWorksT PDMPO an ideal pH probe for acidic organelles with pKa = 4.47. Additionally, the very large Stokes shift and excellent photostability of RatioWorksT PDMPO make it an excellent fluorescent acidotropic reagent for fluorescence imaing and flow cytometry applications. The unique fluorescence properties of RatioWorksT PDMPO might give researchers a new tool with which to study endocytosis, phagocytosis and acidic organelles of live cells. RatioWorksT PDMPO can be well excited by the violet laser at 405 nm for flow cytometric applications. This RatioWorksT PDMPO SE can be readily used to make a variety of bioconjugates for imaging or flow applications, enabling the specific detection of phagocytosis and endocytosis with reduced signal variability and improved accuracy. These conjugates can be also used for multiplexing cell functional analysis with green dyes such as GFP, Fluo-8, calcein, or FITC-labeled antibodies. The short emission band of RatioWorksT PDMPO is ~450 nm while the longer emission is ~550 nm, making the common filter sets of Pacific Blue and Pacific Orange readily available to the assays of RatioWorksT PDMPO.
Supplier: | AAT Bioquest |
Supplier-Nr: | 21211 |
Properties
Application: | FC, PH probe |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed